Pwodwi yo
4-Idroksi-D-(-)-2-phenylglycine
Sinonim:(R,S)-3HPG;4-hydroxyphenylglycine;4-hydroxyphenylglycine hydrobromide, (+-)-isom;4-hydroxyphenylglycine hydrochloride, (R)-izomer;4-hydroxyphenylglycine perchlorate, (+-)-izomer;4 -hydroxyphenylglycine, (+-)-izomè; 4-hydroxyphenylglycine, (R)-izomè; 4-hydroxyphenylglycine, (S)-izomè; 4-hydroxyphenylglycine, 2,4-dimethylbenzenesulfonate, (+-)-izomè; 4-hydroxyphenylglycine , 2,4-dimethylbenzenesulfonate, (R)-izomè; 4-hydroxyphenylglycine, 4-methylbenzenesulfonate, (+-)-izomè; 4-hydroxyphenylglycine, 4-methylbenzenesulfonate, (S)-izomè; 4-hydroxyphenylglycine, sèl monosodyòm; -hydroxyphenylglycine, monosodium sèl, (R)-izomè; Dp-hydroxyphenylglycine; L-4-hydroxyphenylglycine; oxfenicine; p-hydroxyphenylglycine; UK 25842; UK-25842
Pwopriyete chimik D(-)-4-Hydroxyphenylglycine
● Aparans/Koulè:-blan poud
● Presyon vapè: 0.000272mmHg nan 25°C
● Pwen k ap fonn: 240 °C (dec.)(lit.)
● Endèks refraktif:-158 ° (C = 1, 1mol / L HCl)
● Pwen bouyi: 365.8 °C nan 760 mmHg
● PKA:2.15±0.10(Predi)
● Flash Point: 175 °C
● PSA: 83.55000
● Dansite: 1.396 g/cm3
● LogP:1.17690
● Depo Temp.:Magazen anba +30°C.
● Solibilite.:5g/l
● Solibilite dlo.:5 g/L (20 ºC)
● XLogP3:-2.1
● Konte Donatè Kosyon Idwojèn:3
● Konte aseptè kosyon idwojèn:4
● Konte kosyon rotative:2
● Mass egzak: 167.058243149
● Konte Atòm lou:12
● Konpleksite:164
Pite / Kalite
99% * done ki soti nan founisè anvan tout koreksyon
4-Hydroxy-D-(-)-2-phenylglycine *done ki soti nan founisè reyaktif
Enfòmasyon sou sekirite
● Piktogram (yo):
Xi
● Kòd danje: Xi
● Deklarasyon:36/37/38
● Deklarasyon Sekirite: 26-36-24/25
Itil
● SOURI Kanonik: C1=CC(=CC=C1C(C(=O)O)N)O
● SORI Isomerik: C1=CC(=CC=C1[C@H](C(=O)O)N)O
● Itilizasyon: 4-Hydroxy-D-(-)-2-phenylglycine se yon konpoze ki itilize sitou pou preparasyon sentetik antibyotik β-lactam.4-Hydroxy-D-(-)-2-phenylglycine (Cefadroxil EP Impurite A(Amoxicillin EP Impurite A)) se yon konpoze ki itilize sitou pou preparasyon sentetik antibyotik β-lactam.
4-Hydroxy-D-phenylglycine, ke yo rele tou 4-hydroxy-D-phenylglycine oswa 4-HDPG, se yon konpoze chimik ak fòmil molekilè C8H9NO3.Li se yon derive asid amine ak ki dwe nan kategori a nan phenylglycines.4-Hydroxy-D-phenylglycine se sitou itilize kòm yon blòk bilding nan sentèz la nan konpoze pharmaceutique.Li sèvi kòm yon matyè premyè nan pwodiksyon sèten antibyotik, tankou cefadroxil ak sefradin.Antibyotik sa yo fè pati klas cephalosporin epi yo itilize pou trete enfeksyon bakteri.Anplis de wòl li kòm yon précurseur nan sentèz pharmaceutique, 4-Hydroxy-D-phenylglycine te envestige tou pou pwopriyete potansyèl li yo terapetik.Rechèch sijere ke li ka gen efè antioksidan ak anti-enflamatwa, ki ta ka fè li itil nan devlopman nouvo dwòg pou divès kondisyon medikal.An jeneral, 4-Hydroxy-D-phenylglycine se yon konpoze chimik ak aplikasyon enpòtan nan sentèz pharmaceutique ak potansyèl itilizasyon terapetik.Wòl li kòm yon blòk bilding nan pwodiksyon an nan antibyotik mete aksan sou siyifikasyon li nan endistri pharmaceutique la.
